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Neuroblastoma whole sodium (TTX sensitive sodium channels)
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Standard throughput time | 2-4 weeks (draft) |
Source | mouse |
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Expression system | mammalian N1E-115 (NaV1.1, NaV1.2, NaV1.3, NaV1.6, NaV1.7) |
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Method | manual and automated patch-clamping |
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Quality level | high quality functional assay |
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Reference | Carbamazepine (IC50: 398.6 µM) |
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References, further examples | TTX | |
+ Neuronal sodium channel assay |
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+ Antinociceptive screening (CNS / dorsal root ganglion) |