Swiss Quality in Ion channel Services

Nav1.8

Gene: SCN10A

nav1.8 Standard throughput time 2-4 weeks (draft)
Source human
Expression system mammalian (HEK 293)
Method manual and automated patch-clamping
Quality level high quality functional assay
Reference A-803467 (IC50: 42 nM), Tetracaine (IC50: 2.9 µM)
+  Neuronal sodium channel assay
+  Antinociceptive screening (CNS / dorsal root ganglion)
+  CNS toxiticity / safety relevant ion channel test