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Gene: SCN10A
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Standard throughput time | 2-4 weeks (draft) |
| Source | human | |
| Expression system | mammalian (HEK 293) |
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| Method | manual and automated patch-clamping |
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| Quality level | high quality functional assay |
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| Reference | A-803467 (IC50: 42 nM), Tetracaine (IC50: 2.9 µM) |
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| + Neuronal sodium channel assay |
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| + Antinociceptive screening (CNS / dorsal root ganglion) | ||
| + CNS toxiticity / safety relevant ion channel test |
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