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KVLQT1/mink
Gene: KCNQ1 / KCNE1
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Standard throughput time | 2-4 weeks (draft) |
| Source | human | |
| Expression system | mammalian (HEK 293), stable expression | |
| Method | manual and automated patch-clamping |
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| Quality level | high quality functional assay |
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| Reference | Chromanol 293B (IC50: 6.2 µM) |
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References, further examples |
HMR 1556 (IC50: 0.1 µM), Mefloquine (IC50: 3.6 µM) |
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| + Cardiac toxicity / safety relevant ion channel test |
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| + Antiarrhytmic screening |
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