BSYS | hERG (CHO)

hERG

Gene: KCNH2

	Standard throughput time	2 weeks
	Source	human
	Expression system	mammalian (CHO, HEK 293), stable expression
	Method	manual and automated patch-clamping
	Quality level	high quality functional assay
	References	E-4031
	Further References	Dofetilide, Terfenadine, Ketoconazole
	Additional readouts	solubility check, stability check
	+ Should be used for quality characterization of hERG interaction
	+ IKr screen