Swiss Quality in Ion channel Services


Gene: KCNH2

herg Standard throughput time 2 weeks
Source human
Expression system mammalian (CHO, HEK 293), stable expression
Method manual and automated patch-clamping
Quality level high quality functional assay
References E-4031
Further References Dofetilide, Terfenadine, Ketoconazole
Additional readouts solubility check, stability check
+  Should be used for quality characterization of hERG interaction
+  IKr screen