Swiss Quality in Ion channel Services

Cav1.2 CiPA GLP

Gene: CACNA1C

GLP CaV1.2 CiPA peak current Standard throughput time 2 weeks (draft report)
Source human
Expression system mammalian (CHO)
Method manual patch-clamping
Assay temperature Room temperature
36°C ± 1
Reference Nifedipine:
IC50 (peak) = 76.43nM
IC50 (late) = 91.90nM
Verapamil:
IC50 (peak) = 10.39µM
IC50 (late) = 7.82µM
Additional options Solubility tests
Dose range finding
Full glass equipment
Dose formulation analysis can be provided as multisite study with a company on the same campus or any other GLP certified analytical lab.
For further information, please contact us at [email protected]