CiPA

Swiss Quality in Ion channel Services

Neuroblastoma whole sodium (TTX sensitive sodium channels)

 

N1E_sodium Standard throughput time 2-4 weeks (draft)
Source mouse
Expression system mammalian N1E-115 (NaV1.1, NaV1.2, NaV1.3, NaV1.6, NaV1.7)
Method manual and automated patch-clamping
Quality level high quality functional assay
Reference Carbamazepine (IC50: 398.6 µM)
References, further examples TTX
+  Neuronal sodium channel assay
+  Antinociceptive screening (CNS / dorsal root ganglion)