Cambridge bioscience

Contact Person:
Vashu Pamnani


Swiss Quality in Ion channel Services

GLP testing B'SYS specially trained study directors provide guideline compliant recordings at physiologic conditions. GLP testing includes concentration verification of dose solutions. Standardized procedures lead to precise data and rapid study accomplishment.
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Safety services B'SYS performs tests to identify drug interactions with cardiac ion channels that act as target for QT prolongation. Central nervous safety tests involve targets that are involved in addiction and neurotoxicity.
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Discovery services Ion channel subtype selectivity is assessed using the B'SYS  panel of ion channel subsets providing the basis for selectivity screens.  The important issue of ion channel state dependency is particularly important in assessing effects on sodium- and calcium channels:  the therapeutic usefulness and action of compounds is determined by their ability to bind in defined electrical states.
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