CiPA

Swiss Quality in Ion channel Services

GABAA6β3d)

Gene: GABRA6 /GABRB3 /GABRD

gaba a6
Standard throughput time 6 weeks (draft)
Source human
Expression system mammalian (CHO), transient expression
Method whole cell patch-clamping
Quality level high quality functional assay
Reference positive allosteric modulator: Pento barbital (EC50=952µM)
  antagonist: Bicuculline (IC50: 146.3 nM)
References, further examples positive allosteric modulator Alphaxolone