CiPA

Swiss Quality in Ion channel Services

Nav1.3

Gene: SCN3A

nav1.3 Standard throughput time 2-4 weeks (draft)
Source human
Expression system mammalian (CHO, HEK 293)
Method manual and automated patch-clamping
Quality level high quality functional assay
Reference TTX (IC50: 5.2 µM)
+  Neuronal sodium channel assay
+  CNS toxicity / safety relevant ion channel test