B'SYS operates a Sophion QPatch™ for automated patch clamp recordings.

Depending on the dosing scheme and type of ion channel the automated patch clamp setups at B'SYS allow the measurement of 50-100 compounds per day.

Assays and application schemes can be adapted to your needs.

Please contact us for details or offers: [email protected]

Assays available:

 

Target	Service available	Cell line for sale	Host cell line
hERG	X	X	CHO
Kv1.1	X	X	CHO
Kv1.2	X	X	CHO
Kv1.3	X	X	CHO
Kv1.4	X	X	CHO
Kv1.5	X	X	CHO
Kv1.6	X	X	CHO
Kv2.1	X	X	CHO
Kv2.2	X	X	CHO
Kv4.3	X	X	CHO / HEK 293
Kv4.3 / ChIP2	X	X	CHO
Kv7.1 / minK	X	X	CHO / HEK 293
Kir 2.1	X	X	CHO
Nav1.1	X	---	HEK 293
Nav1.2	X	---	HEK 293
Nav1.3	X	X	CHO
Nav1.5	X	X	CHO
Nav1.6	X	---	CHO
Nav1.7	X	---	CHO
Nav1.8	X	X	HEK 293
Cav1.2	X	X	HEK 293
Cav3.2	X	X	HEK 293
HCN4	X	X	HEK 293
CFTR	X	X	CHO / HEK 293
GRIK2	X	X	CHO / HEK 293
NMDA (NR1/2A)	X	X	HEK 293
NMDA (NR1/2B)	X	X	HEK 293
GABAA (α1β2γ2)	X	---	CHO / Ltk
GABAA (α1β3γ2)	X	---	HEK 293
GABAA (α2β2γ2)	X	---	Ltk
GABAA (α3β2γ2)	X	---	Ltk
GABAA (α5β2γ2)	X	---	Ltk
GABAA (β3)	X	X	HEK 293
nAChR (α4β2)	X	X	CHO
TRPV1	X	X	CHO / HEK 293
TRPM8	X	X	CHO / HEK 293
GlyRα3	X	X	CHO / HEK 293
P2X2	X	X	CHO
P2X4	X	X	HEK 293
P2X7	X	X	HEK 293
ASIC 1A / 1B / 3	X	X	CHO
5HT3A	X	X	CHO / HEK 293

 

 

Further assays will be transfered from manual patch clamping to automated patch clamping.

You are missing an assay? Please contact us! [email protected]