CiPA

Swiss Quality in Ion channel Services

KV4.3 (IKto)

Cell lines available: CHO, constitutive expression. Assays validated for manual and automated patch-clamp.

 

Manual patch-clamp:

kv4.3

 

 

IC50 value (µM)

 

IC50 value (µM)

Dapoxetine HCl
instantaneous

12.4

Dapoxetine HCl
Steadystade

3.0

 

 

Automated patch-clamp :

kv4.3cp2

 

 

IC50 value (µM)

Dapoxetine HCl instantaneous

46.3