CiPA

Swiss Quality in Ion channel Services

Kir2.1

Cell lines available: CHO, constitutive expression. Assays validated for manual and automated patch-clamp.

 

Manual patch-clamp:

kircp

 

 

IC50 value (µM)

 

IC50 value (µM)

ML 133 HCl pH 7.4

2.7

ML 133 HCl pH 8.5

0.3

 

 

Automated patch-clamp:

kircp2

 

 

IC50 value (µM)

 

IC50 value (µM)

ML 133 HCl pH 7.4

3.8

ML 133 HCl pH 8.5

0.3